August 31 marks IOAD, a global campaign to end overdose. Partner with us to empower your community.
Use ENGAGE to guide youth substance use prevention efforts in your community.
View fatal and nonfatal overdose data dashboards, and pharmacy dispensing rate maps.
Drug use and mental health challenges are connected. Discover tools to support teens and parents.
For Health Care Professionals
Resources for health care providers on pain management, opioids, and opioid use disorder.
Overview of the intended use for 2022 Clinical Practice Guideline for prescribing opioids for pain.
Clinician trainings on pain management, opioid use disorder, naloxone, and substance use disorders.
For Public Health Professionals
The hub for CDC's Overdose Data to Action program, including information and resources.
Learn about CDC's Drug-Free Communities Support Program and access related resources.
Xylazine is a non-opioid sedative or tranquilizer. Xylazine is not approved for use in people.
Find overdose prevention and intervention resources for public health professionals.
CDC is committed to addressing health inequities and to ensuring health equity.
Overdose Resource Exchange (ORE)
Information on overdose prevention strategies and partnerships for healthcare professionals.