Table 2.1 – Acute Hepatitis B: Numbers & Rates of Cases

At a glance

The national rate of reported acute hepatitis B was 0.6 cases per 100,000 population during 2021.
CDC 2021 Hepatitis B Surveillance Report

Numbers and rates* of reported cases of acute hepatitis B virus infection, by state or jurisdiction — United States, 2017–2021

Numbers and rates* of reported cases† of hepatitis A, by state or jurisdiction — United States, 2018–2022

Source: CDC, National Notifiable Diseases Surveillance System.

* Rates per 100,000 population. Beginning in 2021, single-race population estimates are used for rate calculations. For prior years, bridged-race population estimates are used.

† Reported confirmed cases. For the case definition, see Acute Hepatitis B.

—: No reported cases. The reporting jurisdiction did not submit any cases to CDC.

U: Unavailable. The data were unavailable.

Summary

The capacity for notifying CDC of acute hepatitis B virus infection cases varies considerably based on laws, resources, and infrastructure for conducting viral hepatitis surveillance in each jurisdiction. In 2021, no cases of acute hepatitis B were reported to CDC by Connecticut or Hawaii, and cases from the District of Columbia and Rhode Island were unavailable.

The national rate of reported acute hepatitis B was 0.6 cases per 100,000 population during 2021. West Virginia had the highest rate of acute hepatitis B during 2021 (3.0 cases per 100,000 population), followed by Florida and Maine (2.4 cases per 100,000 population, respectively); Florida also reported the largest number of cases (n = 531).