At a glance
The respiratory vaccine codes and crosswalk tables for RSV, COVID-19, and Influenza are provided in the following summary tables.
Respiratory Syncytial Virus (RSV) Codes and Crosswalks
The following table includes the RSV codes and crosswalks included in the CDC IIS Vaccine Code Sets. Note that the CPT codes shown are not mapped to the NDC codes, but are mapped to the CVX codes shown. CPT codes provided in the vaccine code sets are to assist with code categorizations and are not intended to represent billable codes.
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Download the RSV Crosswalk table
Respiratory Syncytial Virus (RSV) Vaccine Codes Fall Season
| CVX Code | CVX Description | Sale Proprietary Name | Sale Labeler | MVX Code | Unit of Sale NDC11 | Unit of Use NDC11 | Presentation | CPT Code | CPT Description |
|---|---|---|---|---|---|---|---|---|---|
| 303 | Respiratory syncytial virus (RSV), vaccine, recombinant, protein subunit RSV prefusion F, adjuvant reconstituted, 0.5 mL, preservative free | Arexvy | GlaxoSmithKline Biologicals SA | SKB | 58160-0848-11 | 58160-0723-03 | VIAL, 0.5 mL, reconstituted | 90679 | Respiratory syncytial virus vaccine, preF, recombinant, subunit, adjuvanted, for intramuscular use |
| 305 | Respiratory syncytial virus (RSV), vaccine, bivalent, protein subunit RSV prefusion F, diluent reconstituted, 0.5 mL, preservative free | Abrysvo | Pfizer Laboratories Div Pfizer Inc | PFR | 00069-0344-01 00069-0344-05 00069-0344-10 |
00069-0207-01 | VIAL, 0.5 mL, reconstituted | 90678 | Respiratory syncytial virus vaccine, preF, subunit, bivalent, for intramuscular use |
| 305 | Respiratory syncytial virus (RSV), vaccine, bivalent, protein subunit RSV prefusion F, diluent reconstituted, 0.5 mL, preservative free | Abrysvo | Pfizer Laboratories Div Pfizer Inc | PFR | 00069-2465-01 00069-2465-10 |
00069-2465-19 | VIAL, 0.5 mL, SINGLE-DOSE | 90678 | Respiratory syncytial virus vaccine, preF, subunit, bivalent, for intramuscular use |
| 326 | Respiratory syncytial virus (RSV), mRNA, injectable, preservative free | mRESVIA | Moderna US, INC. | MOD | 80777-0345-90 80777-0345-96 80777-0345-61 80777-0345-62 80777-0345-63 |
80777-0345-01 | SYRINGE, 0.5 mL | 90683 | Respiratory syncytial virus vaccine, mRNA lipid nanoparticles, for intramuscular use |
Respiratory Syncytial Virus (RSV) Monoclonal Antibody Codes Fall Season (*)
| CVX Code | CVX Description | Sale Proprietary Name | Sale Labeler | MVX Code | Unit of Sale NDC11 | Unit of Use NDC11 | Presentation | CPT Code | CPT Description |
|---|---|---|---|---|---|---|---|---|---|
| 306 | Respiratory syncytial virus (RSV) monoclonal antibody, IgG1κ, (nirsevimab-alip), 0.5 mL, neonates and children to 24 months | BEYFORTUS | Sanofi Pasteur Inc. | PMC | 49281-0575-15 | 49281-0575-00 | SYRINGE, 0.5 mL | 90380 | Respiratory syncytial virus, monoclonal antibody, seasonal dose; 0.5 mL dosage, for intramuscular use |
| 307 | Respiratory syncytial virus (RSV) monoclonal antibody, IgG1κ, (nirsevimab-alip), 1 mL, neonates and children to 24 months | BEYFORTUS | Sanofi Pasteur Inc. | PMC | 49281-0574-15 | 49281-0574-88 | SYRINGE, 1 mL | 90381 | Respiratory syncytial virus, monoclonal antibody, seasonal dose; 1 mL dosage, for intramuscular use |
| 332 | Respiratory syncytial virus (RSV), monoclonal antibody, IgG1κ, (clesrovimab-cfor), 0.7 mL, neonate and infant, preservative free | ENFLONSIA | Merck Sharp & Dohme LLC | MSD | 00006-5073-01 00006-5073-02 |
00006-5073-99 | SYRINGE, 0.7 mL | 90382 | Respiratory syncytial virus, monoclonal antibody, seasonal dose, 0.7 mL, for intramuscular use |
(*) The BEYFORTUS nirsevimab and ENFLONSIA clesrovimab monoclonal antibody codes are included in the vaccine code set in a manner similar to regular vaccines to enable reporting or other program data exchange in accordance with ACIP and CDC guidelines.
Respiratory Syncytial Virus (RSV) Unspecified Codes
| CVX Code | CVX Description | CVX Note |
|---|---|---|
| 314 | Respiratory syncytial virus (RSV) vaccine, unspecified | Unspecified, for historic records where the specific vaccine administered is not known |
| 315 | Respiratory syncytial virus (RSV) monoclonal antibody (MAB), unspecified | Unspecified, for historic records where the specific RSV MAB administered is not known |
| 304 | Respiratory syncytial virus (RSV), unspecified | Unspecified, for historic records where it is not known if RSV vaccine or RSV MAB was administered |
Fall 2025 COVID-19 Vaccine Codes and Crosswalks
The following table provides a preview and summary of the vaccine codes and crosswalks for Fall 2025 COVID-19 vaccines.
Note: Vaccine codes in the following table are effective upon Food and Drug Administration (FDA) approval and BLA licensure of COVID-19 vaccine(s). The codes are added to the CDC full vaccine code files once FDA DailyMed and FDA drug file listings are published and accessible. Additional code details and field values are included in the full vaccine code sets published.
Download the COVID-19 Vaccine Code Crosswalk table
| Manufacturer (MVX) | Product Label Tradename | CVX Code | CVX Term Description | CVX Short Description | NDC Virus Strain | UoS NDC10 UoS NDC11 |
Packaging | UoU NDC10 UoU NDC11 |
Age Cohort(1)
Presentation |
CPT Code | CPT Description |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pfizer (PFR) |
COMIRNATY (COVID-19 Vaccine, mRNA, 2025-2026 Formula), no freeze formulation | 309 | SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, tris-sucrose, 30 mcg/0.3 mL dose | COVID-19, mRNA, LNP-S, PF, tris-sucrose, 30 mcg/0.3 mL | SARS-CoV-2 virus strain Omicron LP.8.1 | 0069-2528-10 00069-2528-10 |
CARTON, 10 PRE-FILLED GLASS SYRINGES | 0069-2528-01 00069-2528-01 |
Ages 12 years and older.
SYRINGE, PRE-FILLED, GLASS, 30 mcg/0.3 mL - DO NOT FREEZE |
91320 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, spike protein, 30 mcg/0.3 mL dosage, tris-sucrose formulation, for intramuscular use |
| Pfizer (PFR) |
COMIRNATY (COVID-19 Vaccine, mRNA, 2025-2026 Formula) | 310 | SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, tris-sucrose, 10 mcg/0.3 mL dose | COVID-19, mRNA, LNP-S, PF, tris-sucrose, 10 mcg/0.3 mL | SARS-CoV-2 virus strain Omicron LP.8.1 | 0069-2501-10 00069-2501-10 |
CARTON, 10 SINGLE-DOSE VIALS | 0069-2501-01 00069-2501-01 |
Ages 5 through 11 years.
VIAL, SINGLE-DOSE, 10 mcg/0.3 mL |
91319 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, spike protein, 10 mcg/0.3 mL dosage, tris-sucrose formulation, for intramuscular use |
| Moderna (MOD) |
SPIKEVAX (COVID-19 Vaccine, mRNA, 2025-2026 Formula) | 312 | SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 50 mcg/0.5 mL dose | COVID-19, mRNA, LNP-S, PF, 50 mcg/0.5 mL | SARS-CoV-2 virus strain Omicron LP.8.1 | 80777-112-96 80777-0112-96 |
CARTON, 10 PRE-FILLED SYRINGES | 80777-112-01 80777-0112-01 |
Ages 12 years and older.
SYRINGE, PRE-FILLED, 50 mcg/0.5 mL |
91322 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, 50 mcg/0.5 mL dosage, for intramuscular use |
| 80777-112-93 80777-0112-93 |
CARTON (Blister Pack), 10 PRE-FILLED SYRINGES | ||||||||||
| 80777-112-88 80777-0112-88 |
CARTON, 2 PRE-FILLED SYRINGES | ||||||||||
| Moderna (MOD) |
mNEXSPIKE (COVID-19 Vaccine, mRNA, 2025-2026 Formula) | 334 | SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 10 mcg/0.2 mL dose | COVID-19, mRNA, LNP-S, PF, 10 mcg/0.2 mL | SARS-CoV-2 virus strain Omicron LP.8.1 | 80777-400-60 80777-0400-60 |
CARTON, 10 PRE-FILLED SYRINGES | 80777-400-17 80777-0400-17 |
Ages 12 years and older.
SYRINGE, PRE-FILLED, 10 mcg/0.2 mL |
91323 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, 10 mcg/0.2 mL dosage, for intramuscular use |
| 80777-400-61 80777-0400-61 |
CARTON, 2 PRE-FILLED SYRINGES | ||||||||||
| 80777-400-62 80777-0400-62 |
CARTON, 1 PRE-FILLED SYRINGES | ||||||||||
| Moderna (MOD) |
SPIKEVAX (COVID-19 Vaccine, mRNA, 2025-2026 Formula) | 311 | SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 25 mcg/0.25 mL dose | COVID-19, mRNA, LNP-S, PF, 25 mcg/0.25 mL | SARS-CoV-2 virus strain Omicron LP.8.1 | 80777-113-80 80777-0113-80 |
CARTON, 10 PRE-FILLED SYRINGES | 80777-113-09 80777-0113-09 |
Ages 6 months through 11 years.
SYRINGE, PRE-FILLED, 25 mcg/0.25 mL |
91321 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, 25 mcg/0.25 mL dosage, for intramuscular use |
| 80777-113-87 80777-0113-87 |
CARTON, 2 PRE-FILLED SYRINGES | ||||||||||
| Novavax (NVX) |
NUVAXOVID (COVID-19 Vaccine, Adjuvanted 2025-2026 Formula) |
313 | SARS-COV-2 (COVID-19) vaccine, subunit, recombinant spike protein-nanoparticle+Matrix-M1 Adjuvant, preservative free, 5 mcg/0.5 mL dose | COVID-19, subunit, rS-nanoparticle, adjuvanted, PF, 5 mcg/0.5 mL | SARS-CoV-2 virus strain Omicron JN.1 | 80631-207-10 80631-0207-10 |
CARTON, 10 PRE-FILLED SYRINGES | 80631-207-01 80631-0207-01 |
Ages 12 years and older.
SYRINGE, PRE-FILLED, 5 mcg/0.5 mL |
91304 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, recombinant spike protein nanoparticle, saponin-based adjuvant, preservative free, 5 mcg/0.5 mL dosage, for intramuscular use |
- All vaccines listed above are approved under BLA licensure by the FDA effective 08/27/2025.
- Emergency Use Authorizations (EUA) for the 2024 Fall season vaccines have been revoked by the FDA effective 08/27/2025.
- (1) FDA approved age cohort for each vaccine formulation is shown, subject to eligibility guidance from FDA and CDC.
Other COVID-19 Vaccine Related Codes and Links
FDA has revoked all COVID-19 EUA vaccine authorizations effective 08/27/2025.
EUA Recipient and Caregiver Fact Sheet URLs and Document Codes in 2D Barcodes are no longer active.
Beginning with the FDA approval of Fall 2025 COVID-19 vaccines under BLA effective 08/27/2025, vaccine NDCs, lot numbers, expiration dates, and other relational information will no longer be maintained in the CDC COVID-19 Vaccine Lot Number and Expiration Date Report used to communicate this information under EUA. Registered users may continue to access this COVID-19 vaccine lot number and expiration date relational information provided to CDC by the vaccine manufacturers for historic immunization recordkeeping purposes.
2025/2026 Seasonal Influenza Codes and Crosswalk
This format includes all seasonal influenza vaccines for the season in a single Excel crosswalk table that provides the CVX, MVX, NDC Unit of Sale, NDC Unit of Use, and CPT (*) codes for each vaccine.
(*) Please note that the CPT codes shown for each vaccine crosswalk are not mapped to the NDC codes, but are mapped to the CVX codes shown. These are reference CPT codes for vaccine categorization and are not intended to represent billable codes.
Download the Seasonal Influenza Crosswalk table
Influenza Vaccines for Season 2025/2026 (Northern Hemisphere)
168Influenza, adjuvanted, trivalent, PFInfluenza, adjuvanted, inactivated, trivalent, injectable, preservative freeFLUADSeqirus, Inc.SEQ70461-025-03
70461-0025-0370461-025-04
70461-0025-04SYRINGE, 0.5mL90653Influenza vaccine, inactivated (IIV), subunit, adjuvanted, for intramuscular use
| CVX Code | CVX Short Description | CVX Long Name | Sale Proprietary Name | Sale Labeler | MVX Code | Sale Unit (UoS) NDC10 NDC11 |
Use Unit (UoU) NDC10 NDC11 |
Presentation | CPT Code | CPT Description |
|---|---|---|---|---|---|---|---|---|---|---|
| 141 | Influenza, split virus, trivalent, preservative | Influenza, split virus, trivalent, injectable, contains preservative | Afluria | Seqirus PTY LTD. | SEQ | 33332-125-10 33332-0125-10 |
33332-125-11 33332-0125-11 |
VIAL, 5 mL, MULTI-DOSE | 90658 | Influenza virus vaccine, trivalent (IIV3), split virus, 0.5 mL dosage, for intramuscular use |
| 140 | Influenza, split virus, trivalent, PF | Influenza, split virus, trivalent, injectable, preservative free | Afluria | Seqirus PTY LTD. | SEQ | 33332-025-03 33332-0025-03 |
33332-025-04 33332-0025-04 |
SYRINGE, 0.5 mL | 90656 | Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, 0.5 mL dosage, for intramuscular use |
| 168 | Influenza, adjuvanted, trivalent, PF | Influenza, adjuvanted, inactivated, trivalent, injectable, preservative free | FLUAD | Seqirus, Inc. | SEQ | 70461-025-03 70461-0025-03 |
70461-025-04 70461-0025-04 |
SYRINGE, 0.5mL | 90653 | Influenza vaccine, inactivated (IIV), subunit, adjuvanted, for intramuscular use |
| 140 | Influenza, split virus, trivalent, PF | Influenza, split virus, trivalent, injectable, preservative free | FLUARIX | GlaxoSmithKline Biologicals SA | SKB | 58160-912-52 58160-0912-52 |
58160-912-41 58160-0912-41 |
SYRINGE, 0.5mL | 90656 | Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, 0.5 mL dosage, for intramuscular use |
| 155 | Influenza, recombinant, trivalent, PF | Influenza, recombinant, trivalent, injectable, preservative free | FLUBLOK TRIVALENT NORTHERN HEMISPHERE | Sanofi Pasteur Inc. | PMC | 49281-725-10 49281-0725-10 |
49281-725-88 49281-0725-88 |
SYRINGE, 0.5 mL | 90673 | Influenza virus vaccine, trivalent (RIV3), derived from recombinant DNA, hemagglutinin (HA) protein only, preservative and antibiotic free, for intramuscular use |
| 153 | Influenza, MDCK, trivalent, PF | Influenza, Madin Darby Canine Kidney, subunit, trivalent, injectable, preservative free | Flucelvax | Seqirus Inc. | SEQ | 70461-655-03 70461-0655-03 |
70461-655-04 70461-0655-04 |
SYRINGE, 0.5 mL | 90661 | Influenza virus vaccine, trivalent (ccIIV3), derived from cell cultures, subunit, antibiotic free, 0.5 mL dosage, for intramuscular use |
| 320 | Influenza, MDCK, trivalent, preservative | Influenza, Madin Darby Canine Kidney, subunit, trivalent, injectable, contains preservative | Flucelvax | Seqirus Inc. | SEQ | 70461-555-10 70461-0555-10 |
70461-555-11 70461-0555-11 |
VIAL, 5 mL, MULTI-DOSE | 90661 | Influenza virus vaccine, trivalent (ccIIV3), derived from cell cultures, subunit, antibiotic free, 0.5 mL dosage, for intramuscular use |
| 140 | Influenza, split virus, trivalent, PF | Influenza, split virus, trivalent, injectable, preservative free | FLULAVAL | ID Biomedical Corporation of Quebec | IDB | 19515-904-52 19515-0904-52 |
19515-904-41 19515-0904-41 |
SYRINGE, 0.5 mL | 90656 | Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, 0.5 mL dosage, for intramuscular use |
| 135 | Influenza, high-dose, trivalent, PF | Influenza, high-dose, split virus, trivalent, injectable, preservative free | FLUZONE HIGH DOSE NORTHERN HEMISPHERE | Sanofi Pasteur Inc. | PMC | 49281-125-65 49281-0125-65 |
49281-125-88 49281-0125-88 |
SYRINGE, 0.5 mL | 90662 | Influenza virus vaccine (IIV), split virus, preservative free, enhanced immunogenicity via increased antigen content, for intramuscular use |
| 141 | Influenza, split virus, trivalent, preservative | Influenza, split virus, trivalent, injectable, contains preservative | FLUZONE TRIVALENT NORTHERN HEMISPHERE | Sanofi Pasteur Inc. | PMC | 49281-643-15 49281-0643-15 |
49281-643-78 49281-0643-78 |
VIAL, 5 mL, MULTI-DOSE | 90658 | Influenza virus vaccine, trivalent (IIV3), split virus, 0.5 mL dosage, for intramuscular use |
| 140 | Influenza, split virus, trivalent, PF | Influenza, split virus, trivalent, injectable, preservative free | FLUZONE TRIVALENT NORTHERN HEMISPHERE | Sanofi Pasteur Inc. | PMC | 49281-425-50 49281-0425-50 |
49281-425-88 49281-0425-88 |
SYRINGE, 0.5 mL | 90656 | Influenza virus vaccine, trivalent (IIV3), split virus, preservative free, 0.5 mL dosage, for intramuscular use |
| 111 | Influenza, live, trivalent, intranasal, PF | Influenza, live, trivalent, intranasal, preservative free | FluMist trivalent | MedImmune, Inc. (AstraZeneca) |
MED | 66019-112-10 66019-0112-10 |
66019-112-00 66019-0112-00 |
CARTON OF 10 APPLICATOR, 0.2 mL | 90660 | Influenza virus vaccine, trivalent, live (LAIV3), for intranasal use |
| 333 | Influenza, live, trivalent, intranasal, self/caregiver admin, PF | Influenza, live, trivalent, intranasal, self or caregiver administered, preservative free | FluMist trivalent, (self/caregiver administered) | MedImmune, Inc. (AstraZeneca) |
MED | (*) 66019-112-51 66019-0112-51 |
(*) 66019-112-51 66019-0112-51 |
CARTON OF 1 APPLICATOR, 0.2 mL | (*) NA |
(*) NA |
(*) The Unit of Use (UoU) for FluMist self or caregiver administered vaccine is listed with the same NDC code as the Unit of Sale (UoS) NDC. This allows mapping to a different CVX code for self or caregiver administered FluMist vaccine. A CPT code is not applicable for the self or caregiver NDC billing.
Southern Hemisphere 2025 Influenza Season
| CVX Code | CVX Short Description | CVX Long Name | Sale Proprietary Name | Sale Labeler | MVX Code | Sale Unit (UoS) NDC10 NDC11 |
Use Unit (UoU) NDC10 NDC11 |
Presentation | CPT Code | CPT Description |
|---|---|---|---|---|---|---|---|---|---|---|
| 331 | influenza, Southern Hemisphere, preservative free | Influenza, seasonal, Southern Hemisphere, trivalent, 0.5 mL dose, preservative free | FLUZONE TRIVALENT SOUTHERN HEMISPHERE | Sanofi Pasteur Inc. | PMC | 49281-0325-50 | 49281-0325-88 | SYRINGE, 0.5 mL | NA | NA |
Content Source:
National Center for Immunization and Respiratory Diseases