Registry Plus Software

What to know

Registry Plus is a suite of publicly available free software programs for collecting and processing cancer registry data. The Registry Plus suite can be used separately or together for routine or special data collection.

Background

CDC provides Registry Plus software programs to implement the National Program of Cancer Registries, established by Public Law 102-515.

Hardware requirements

Registry Plus programs work with 32- and 64-bit Microsoft® Windows® operating systems on x86-compatible processors. For more information on hardware requirements, compatibility, and technical support, please see the Registry Plus Knowledgebase.

Technical support

In the United States

Central cancer registries are the primary intended users of Registry Plus. CDC helps states set up the software and perform basic customization. Periodic software updates and problem solving are also provided to the extent of available resources. Our support is provided exclusively by telephone and email. CDC is not staffed to provide on-site services, nor can we support hospitals, clinics, laboratories, or other private users.

Some components of Registry Plus—Abstract Plus, for example—are intended for redistribution after customization. A central registry or other institution redistributing Registry Plus software should provide all support to end users and develop expertise in using the software among its own staff. Other users of Registry Plus software should contract, hire, or develop capability independently to understand and maintain the software applications. Contact your central cancer registry.

Non-NPCR organizations should refer to the Policy and Letter of Agreement for Use of CDC-Developed Software by Users External to the National Program of Cancer Registries.

Outside the United States

The Registry Plus Development group is funded primarily to support NPCR-funded central cancer registries, and cannot offer implementation support for Registry Plus products to other countries. However, you are free to download the programs and implement them using other resources.

For more information, please refer to the Policy and Letter of Agreement for Use of CDC-Developed Software by Users External to the National Program of Cancer Registries.

Please note that data items and codes in Abstract Plus are in English, and are based on North American Association of Central Cancer Registries (NAACCR) Standards for Cancer Registries, Volume II, Data Standards and Data Dictionary.

Suggested citation

Registry Plus, a suite of publicly available software programs for collecting and processing cancer registry data. Atlanta (GA): US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion; 2025. Available at: www.cdc.gov/national-program-cancer-registries/registry-plus/. Accessed month/day/year.

Registry Plus components

Abstract Plus

A cancer data collection tool that is used to summarize medical records into an electronic report of cancer diagnosis and treatment.

CRS Plus and TLC Plus

CRS Plus is the main central registry database program, and TLC Plus is an automated tumor linkage and consolidation function.

Link Plus

A standalone probabilistic record linkage program that can detect duplicates in a cancer registry database and link a cancer registry file with external files.

NOAH

The National Oncology rapid Ascertainment Hub (NOAH) helps central cancer registries identify reportable cancer cases in pathology reports.

Prep Plus

A program for the central cancer registry that receives NAACCR-formatted abstracts and incorporates them into the central database.

Web Plus

Collects cancer data securely over the public Internet to support online abstracting, file upload and download, and follow-back efforts.

Web Plus Admin Tool

Allows administrators to export abstracts and uploaded files out of Web Plus, as well as to run edits on uploaded files.

eMaRC Plus

Receives and processes HL7 files from pathology laboratories, and reports from physician offices in HL7 CDA format.

Exchange Plus

A tool for reading and writing data exchange files formatted according to the NAACCR XML Data Exchange Standard Implementation Guide.

Utility Programs

Small programs that perform a variety of useful functions for Registry Plus programs. They are implemented as dynamic link libraries (DLLs).