Rates^* of reported cases^† of acute Hepatitis B virus infection, by age group — United States, 2006–2021

Since 2011, rates of reported cases of acute hepatitis B remained low and decreased among children and adolescents aged 0-19 years and persons aged 20-29 years. This is likely explained, in part, because of the implementation of childhood hepatitis B vaccine recommendations first published in 1991. As the cohort of persons vaccinated as children have grown older, rates of acute hepatitis B among persons aged 30-39 years began to consistently decrease beginning in 2015.

Conversely, rates of reported cases of acute hepatitis B have steadily increased among persons aged 40-49, 50-59 years, and 60 years and older from 2015-2019. In 2020, rates declined in all adult age groups. In 2021, rates among all age groups remain stable or declined compared to 2020. The highest rates were among persons 40-49 years (1.6 cases per 100,000 population) and 50-59 years (1.0 case per 100,000 population).